Early Clinical Development Medical Director, Oncology

GSK

Pharmaceutical Industry

Zug - Schweiz

Manager / Team Leader

Experteer Overview

In this role you will bridge preclinical discovery and clinical development to advance prostate cancer therapies. You will lead medical input and data generation across early-phase trials, engaging with external experts and cross-functional teams to de-risk translation. You will oversee trial design, safety monitoring, and regulatory interactions, supporting regulatory filing and lifecycle management. The position combines scientific leadership with strategic partnership-building in a global Oncology portfolio.

Compensation / Benefits

annual bonus
share-based long term incentive program
healthcare and family insurance
retirement benefits
paid holidays and vacation
paid caregiver/parental and medical leave

Responsibilities

Collaborate with cross-functional teams to develop and execute early phase interventional trials for prostate cancer.
Ensure high-quality protocol development aligned with the Clinical Development Plan and product differentiation goals.
Contribute to end-to-end trial processes from protocol concept to final study report, ensuring alignment with regulatory and development strategies.
Interpret and summarize safety, efficacy, PK/PD, and patient-reported outcomes relevant to the prostate cancer population.
Provide medical oversight for trials, including eligibility assessment, design questions, and urgent safety issues; incorporate Safety/PV as relevant.
Medical review of trial data and oversight of data packages for internal/external IDMCs.
Monitor safety data in collaboration with pharmacovigilance for active studies.
Co-author clinical study reports and regulatory documents; collaborate with Regulatory Affairs, CMC, Toxicology, Research, Pharmacology.
Collaborate with Principal Investigators on dose escalation/expansion studies and publications.
Develop long-term strategic partnerships with external thought leaders to support GSK’s vision.
Understand biology, clinical strategy, and literature related to target diseases and mechanisms.
Serve as a core member of the Clinical Matrix Team and participate in disease area strategy and medical affairs initiatives.
Represent Clinical Development on disease area strategy and Integrated Evidence/Medical Affairs teams.
Participate in Oncology Clinical Development-wide initiatives and workstreams.

Key requirements

Medical degree from accredited medical school
Completion of a clinical residency program
Experience in clinical research and development in Oncology
Experience working in the pharmaceutical/biotechnology industry in prostate cancer

Leadership and people management Strong communication and cross-functional collaboration Strategic thinking and problem solving Oncology clinical trial design and execution Data review/interpretation and clinical data analysis GCP principles and regulatory requirements for registration