Director, Clinical Science
Monte Rosa Therapeutics
Human Health and Social Work
Boston, MA - USA
Manager / Team Leader
Experteer Overview
As Director Clinical Scientist you drive scientific oversight and data integrity for early-stage programs within Clinical Development. You are the main clinical contact for internal and external stakeholders, shaping development strategy and providing senior-level recommendations. You will lead clinical execution, contribute to protocol development, and translate data into actionable insights for senior management. This role offers meaningful impact through advancing oncology/immunology programs and enabling high-quality clinical practice through collaboration and innovation.
Responsibilities
- Lead clinical execution of one or more studies and, where applicable, serve as clinical lead for early-phase programs
- Develop and refine study protocols and amendments with high quality delivery
- Oversee key regulatory documents (ICD, Investigator Brochure, Investigator Letters, safety documents)
- Provide scientific/medical guidance to study teams and CROs
- Review SAE data and manage safety/regulatory documentation; present data to Safety Review Team
- Collaborate with translational scientists to align clinical questions with pre-clinical data
- Contribute to publication strategy and author/review Clinical Study Reports
- Represent the project in Site Initiation Visits and ensure protocol understanding
- Analyze dose-related safety data and support dose-issue governance in collaboration with program physicians
- Build and maintain investigator/site networks to support start-up and execution
- Engage in external scientific alliances and present clinical expertise to stakeholders
Key requirements
- 8+ years in clinical drug development or medical research in pharma/biotech or academia
- Oncology or immunology experience
- Strong understanding of cancer biology and evolving clinical practice
- Proven leadership and senior-level influence within matrix teams
- Excellent communication, presentation, and organizational skills
- Proven scientific writing ability
- Experience coordinating externally with contracts and scientific engagements
- Ability to work proactively, independently and mentor junior staff
- Comfort with AI and evolving technologies to improve clinical practice
Description
As Director Clinical Scientist you drive scientific oversight and data integrity for early-stage programs within Clinical Development. You a…
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